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In 2004, founding chief executive officer Steve Chang decided to split the responsibilities of CEO and chairman of the company. Company co-founder Eva Chen succeeded Steve Chang as chief executive officer of Trend Micro in January 2005. Chen had most recently served as the company's chief technology officer since 1996 and before that executive vice president since the company's founding in October 1989. Steve Chang retained his position as company chairman. In May, Trend Micro acquired Braintree, Massachusetts-based antispyware company InterMute for $15 million. Trend Micro had fully integrated InterMute's SpySubtract antispyware program into its antispyware product offerings by the end of that year. In June 2005 Trend Micro acquired Kelkea, a San Jose, California-based developer of antispam software. Kelkea developed Mail Abuse Prevention System (MAPS) and IP filtering software that allowed internet service providers to block spam and phishing scams. Kelkea chief executive officer Dave Rand was retained by Trend Micro as its chief technologist for content security.

Expert Forecasts for 2020

• The significant gap that must be filled before the scientifically lagging nations can even reach the level of proficiency. But just because a country has the capacity to implement a certain technology application does not mean that it will want or need to. With distinct sets of problems and diverse profiles, different countries will continue to have different national priorities through 2020. Because technology applications are designed to perform specific functions, they pertain only to certain problems. Consequently, not all 16 applications will be equally relevant for all countries. Cheap solar energy, rural wireless communications, GM crops, filters and catalysts, and cheap autonomous housing could help scientifically developing nations promote economic development in rural areas, for the same reasons as in the scientifically lagging countries. The benefits to public health from cheap solar energy, rural wireless communications, GM crops, rapid bioassays, filters and catalysts, cheap autonomous housing, and green manufacturing would also better the health of individuals. In addition, targeted drug delivery, by limiting damage to healthy cells and tissues when administering therapies, would enable less-invasive, debilitating treatments and better outcomes. Improved diagnostic and surgical methods would make diagnoses more precise and surgical procedures more effective, and reduced recovery times would give a wider group of patients the option of surgery. • Quantum cryptography: Quantum mechanical methods that encode information for secure transfer.